Study of Intrathecal Dexmedetomidine and Fentanyl as an Supporting to isobaric Levobupivacaine for Lower Limb Orthopaedic Surgery

Abstract

Administrating the combinations of other classes of analgesics with local anesthetics has used to increase the duration and reduce side effects of analgesia. Some drugs have been used as adjuvants in spinal anesthesia to prolong intraoperative and postoperative analgesia including opioids, α2 agonists, neostigmine, vasoconstrictors, etc. Clonidine and dexmedetomidine are two α2 agonists affecting via pre- and post-synaptic α2 receptors. Hence based on above data the present study was planned for Study of Intrathecal Dexmedetomidine and Fentanyl As An Supporting to isobaric Levobupivacaine for Lower Limb Orthopaedic Surgery.The present study was planned in Department of Anaesthesia, Vardhman Institute of Medical Science Pawapuri. Nalanda, Bihar. The study was conducted from January 2016 to December 2017. In the present total 50 patients undergoing the lower limb orthopaedic surgeries were enrolled. The patients were divided in two study groups based on the administration of dexmedetomidine and fentanyl. The dexmedetomidine appears to be an attractive alternative to fentanyl as an adjuvant to spinal bupivacaine in surgical procedures. It provides good quality of intraoperative analgesia, hemodynamically stable conditions, minimal side effects, and excellent quality of postoperative analgesia.