NSAIDS induced cutaneous adverse drug reaction – a case series

Authors

  • Debajyoti Saha Senior Resident, Egra Superspeciality Hospital, Hospital Road, Katranka, Purba Medinipur, West Bengal 721454, India
  • Sabnam Ara Begum Assistant Professor, Department of Pharmacology, R G Kar Medical College & Hospital, 1, Khudiram Bose Sarani, Kolkata, West Bengal 700004, India
  • Saugata Sarkar Final Year Post Doctoral Trainee, Department of Clinical & Experimental Pharmacology, Calcutta School of Tropical Medicine, 108, Chittaranjan Avenue, Kolkata, West Bengal 700073, India
  • Nabarun Gupta Medical Officer, Swasthya Bhawan, GN-29 Sector-V, Salt Lake, Kolkata, West Bengal 700091, India
  • Sukanta Sen Professor & Head, Department of Pharmacology, ICARE Institute of Medical Sciences and Research, Banbishnupur, Purba Medinipur, Haldia, West Bengal 721645, India
  • Santanu Kumar Tripathi Professor & Head, Department of Clinical & Experimental Pharmacology, Calcutta School of Tropical Medicine, 108, Chittaranjan Avenue, Kolkata, West Bengal 700073, India

Keywords:

NSAIDs, severe cutaneous adverse reactions (SCARs), cutaneous adverse drug reactions (CADRs), stevens johnson syndrome (SJS), fixed drug eruptions (FDEs), fixed dose combination (FDC), over the counter (OTC)

Abstract

Nonsteroidal anti-inflammatory drugs (NSAIDs) are common cause of cutaneous adverse reactions (CADR’s). Though there are fairly high numbers of agents which commonly cause CADR, NSAID’s holds no exception. NSAIDs can cause multiple cutaneous complications like urticaria, angioedema, acneiform eruption, stevens johnson syndrome (SJS), toxic epidermal necrolysis (TEN), vasculitis, fixed drug eruption (FDE) etc. NSAIDs are very frequently prescribed drugs and even one of the frequent over the counter sold medications, thus making it more important to have a more detailed knowledge of the vast cutaneous complications it can cause. The present case series focuses on the conglomeration of the few cases of cutaneous complications experienced by the patients on NSAID’s therapy.

 

Keywords: NSAIDs, severe cutaneous adverse reactions (SCARs), cutaneous adverse drug reactions (CADRs), stevens johnson syndrome (SJS), fixed drug eruptions (FDEs), fixed dose combination (FDC), over the counter (OTC)

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Published

2020-09-11

How to Cite

Saha, D., Begum, S. A., Sarkar, S., Gupta, N., Sen, S., & Tripathi, S. K. (2020). NSAIDS induced cutaneous adverse drug reaction – a case series. International Journal of Health and Clinical Research, 3(5), 6–10. Retrieved from https://ijhcr.com/index.php/ijhcr/article/view/140

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