A observational Study to evaluate visual acuity and clinical ocular profile of patients with pseudoexfoliation syndrome and pseudoexfoliation glaucoma

Abstract

Objective: The main objective of the study was to evaluate visual acuity and clinical ocular profile of patients withpseudoexfoliation syndrome and pseudoexfoliation glaucomaMaterial and Methods: This was an observational retrospective study and patients who were presented with clinical signs of PEX were included in the study. A signed informed consent from was obtained from each and everyparticipants.Comprehensive ophthalmological assessment were done in all participants.Result:610 patients who were having clinical signs of PEX was participated were included in this study and 150 patients had typical characteristics of PEX as well as glaucomatous optic disc changes. The mean age of patients having PEX and PXG was 63.45 ± 7.39 years and majority of patients i.e. 88% were having age more than 50 years (>50) which was significantly higher (p= 0.0001). As compare to females in PEX and PXG proportion of males was significantly higher. 1.46:1 was the ratio of male: female in PEX patients and 2.13:1 was the ration in PXG patients. In patients having PEX and PXG, bilateral involvement of disease were observed in most of the patients. Increased cupping at time of presentation were detected with PXG as observed in Slit lamp biomicroscopy. Cupping of 0.7 were present in 33.3% of patients where as >0.8 cupping of disc were present in 50% of patients.Mean average value of 531 ± 24.32 μm CCT were found in PEX where as it was 521 ± 29.82μm in PXG.Conclusion:In older population prevalence of PEX and PXG were found to be higher. At presentation more severity of optic nerve damage were found in patients with PXG. To minimize the extent of optic nerve damage regular follow-up of patients is required with a careful assessment for detection of PEX.