Comparison of Pseudoexfoliation Syndrome (PXF) and PseudoexfoliationGlaucoma(PXG) by Measuring the Central Corneal Thickness Using Ultrasonic Pachymetry

Abstract

Objective: the main objective of the study was to compare the pseudoexfoliation syndrome (PXF) and pseudoexfoliationglaucoma(PXG) by measuring the central corneal thickness using ultrasonic pachymetry.Material and methods: This is can observational study conducted at ophthalmology out patient department. Patients consent from was obtained before the enrolment and patients who were aged between 30 to 70 of both male and female were included into the study. Patients who were having corneal dystrophies and degenerations, previous ocular surgeries, with the history of ocular trauma and glaucoma without pseudoexfoliation were excluded from the study.Results: 240 patients were evaluated in this observational study. Three groups were formed among which Group I consisted of 70 patients with PXS, Group II consisted of 70 patients with PXG and Group III consisted of 70 healthy controls. The male and female ration of the three groups are 40/30 in group I, 37/33 in group II and 39/31 in Group III. Mean age of Group I,II and III are 63.42 ± 6.54, 65.26 ± 7.63 and 61.12 ± 7.34 years respectively. In different groups between age and sex of patients no significant difference is noticed (p > 0.1). To those with Group 1 and Group 3 as a comparison Group 2 have thinner corneas, the difference being statistically significant (p<0.05). As compared to Group 3 patients in Group 1 had thinner corneas and the difference being statistically insignificant (p=0.432). Conclusion:The study shows that as compare to controls (CNT) and pseudoexfoliation syndrome without glaucoma (PXS) corneas are thinner in patients with pseudoexfolaition glaucoma (PXG).