Evaluation of Vitamin D Levels In Pregnancy Induced Hypertension

Abstract

Background:Pregnancy hypertension increases maternal and foetal morbidity and mortality. Vitamin D deficiency has been identified as a causative factor for hypertension, in addition to other risk factors.Aim:To evaluate the level of serum vitamin D in pregnancy induced hypertension and also to compare with normotensive pregnant women.Material And Methods:This prospective comparative study was conducted in the Department of biochemistry, govt. medical college Kathua India from August 2019 to December 2019. The levels of serum vitamin D were evaluated in fifty pregnant women with hypertension and were compared with equal number of normotensive pregnant women. Pearson's correlation was used to examine the relationship between vitamin D deficiency and hypertension. Comparisons between groups were performed using Student’s t test for continuous variables and the chi-square test for categorical variables. Statistical significance was taken <0.05.
Results: The prevalence of vitamin D deficiency in hypertensive pregnant women was 90% and in normotensive was 82%. Mean vitamin D levels in hypertensive pregnant females were significantly lower than those of normotensive pregnant females. A significant negative correlation was seen between systolic and diastolic blood pressure and vitamin D levels in hypertensive pregnant females.Conclusion: Vitamin D levels are low in Pregnancy induced hypertension patients, and vitamin D deficiency is more common in PIH patients, suggesting that vitamin D deficiency may be a risk factor for the pregnancy induced hypertension.