Diagnostic Laboratory Markers of COVID-19 Positive Patients in a Tertiary Care Hospital of Southern Rajasthan

Abstract

Introduction:As Coronavirus disease is spreading, there is urgent need of identification of clinical and laboratory predictors for progression towards severe and fatal forms of this illness. Corona virus infected people have mild to moderate symptoms. However, 15-32% develops severe symptoms with a case fatality rate of 1-15%. Covid-19 is a systemic infection with adverse impact on hematopoietic system and hemostasis .
Aim: The main aim of this study was to predict common laboratory parameters which are altered in covid-19 positive patients. Methods:A retrospective study was conducted at Geetanjali Medical College and Hospital for 2 months during first wave of Covid-19. The confirmed 101 positive patient’s list was collected from Microbiology DPT. HIS system of GMCH Udaipur. This study includes all common laboratory parameters of Covid-19 diagnosed patients. Laboratory parameters included in this study were – Complete blood count, CRP, D-dimer, A/G ratio, S.Ferritin, S.Creatinine and LDH. The data was collected using HIS system.Conclusion:This study predicted that NLR and S.Ferritin get deranged in majority and were best laboratory markers to look after during COVID period .They should be given ICU care. The next good predictors were CRP, S.Creatinine and D-dimer. The tests of LDH and A: G ratio should be avoided as they are poor tests. This has been decided on the basis of ROC curve.