A study on neutrophil lymphocyte ratio as a prognostic predictor in patient with acute ischaemic stroke visiting tertiary care hospital of southern Bihar

Abstract

Introduction: The Neutrophil- Lymphocyte Ratio (NL Ratio) is one of potential early markers that can be correlated to mortality or morbidity in acute ischaemic stroke , being readily available, cost effective and routinely requested in laboratory Aim and Objectives: To study the clinical presentation and risk factors of acute Ischaemic stroke And To study the pattern of stroke and neutrophil lymphocyte correlation. Methodology: This was a Retrospective study, conducted on 100 study subjects of stroke at medical ward of Narayan medical college and Hospital, Rohtas, South Bihar. Data was collected from the record of Narayan medical college, Rohtas,NLR was calculated as the ratio of neutrophils to lymphocytes in peripheral blood. Result: There was correlation between NLR value of patients and GCS score with R square 0.593. On applying multivariate analysis for seeing the effect of age, Time duration, Total count, and NLR over GCS score, we found significant correlation with R square 0.636.There was also correlation between SSR score and NLR with R square 0.661. On applying multivariate analysis for seeing the effect of age, Time duration, Total count, and NLR over SSS score, we found significant correlation with R square 0.686. Conclusions: An elevated NLR at the time of hospital admission may be a predictor of morbidity and  mortality in acute stroke patients. Because of its routine use, low cost and easy-to-measure nature, NLR can be used for prediction of prognosis and in-hospital mortality in stroke patients.

Keywords: Stroke, NLR, GCS score, SSS score, TIA.