Contrast-Induced Nephropathy: Myth or Reality? Single center experience in patients undergoing planned percutaneous coronary intervention

Abstract

The definition of Contrast-induced nephropathy (CIN) is the impairment of renal function and is measured either as increase in serum creatinine (SCr) by 25% from baseline or 0.5 mg/dL increase in absolute value, within 48-72 hours of intravenous contrast administration.
The objectives were to establish the incidence of CIN and to define the clinical and periprocedural risk factors leading to CIN in patients receiving contrast media.Methods: In a retrospective, observational, descriptive study, patients who were admitted to the hospital for therapeutic Percutaneous Coronary Inervention (PCI) between June 2020 to December 2020, the serum creatinine and glomerular filtration rate (GFR) prior to angiography and 72 hours post procedure were measured. Results: 202 patients were included in the study, of which 4.45 % developed CIN.
Discussion: In our study,the incidence was found to be lower than the literature review. The present study investigated renal function in the chronic phase in patients with ischemic heart disease undergoing planned PCI. The progression of renal dysfunction in patients who develop CIN is thought to result from glomerular overfiltration in the residual nephrons and the release of neurohormones that reduce renal blood flow.