Chronic Kidney Disease of Unknown Etiology at Tertiary Center

Abstract

Introduction: Chronic kidney diseases are a global public health problem associated with premature mortality, decreased quality of life. A trend towards an increase in its incidence and prevalence has been reported worldwide. Chronic renal failure (CRF) is an irreversible deterioration of renal function, which results from diminished effective functioning renal tissue. Materials and Methods: It is a cross sectional and observational study. Research methodology arranges in a systematic way all the components of the study that is more likely to lead to valid answers. It plays a crucial implication for Validity and credibility of the study findings. This chapter gives a brief description of the materials and methods adopted for the study to estimate the incidence of chronic kidney disease of unknown etiology in patients who are admitted at hospital. Results: We found out that 18% (38 patients) had CKDu while diabetes and hypertension were present in 50% and 32% respectively. Males predominated, male to female ratio being 3:1. 24% patients of CKDu belonged to age group of 21-30 years, active age group and 28% were above 31-40 years. Remaining 48% patients were more than 41 years old. Almost 62 % of patients had anemia. 8% patients suffered from CVD and 5% patients had history of CVA. NSAIDS use was seen in 25 % of patients. In our study majority patients presented in stage 4 and stage 5 CKDu with shrunken kidneys. 69% patients were CKDu stage 4 and stage 5 and only 31% patients were stage 1-3, which are represented in the Table 8 and figure 8. Conclusion: Though, contrasting the supplementary registry data, though hypertension occurrence is decreasing likened to earlier years, prolonged glomerulonephritis leftovers the second common reason of CKD and accounts for 16.2%.