A Prospective Study to evaluate the Validity of Pulse Oxymeter Screening for early detection of Congenital heart disease

Abstract

Background: This study was designed to evaluate the effectiveness of routine postnatal clinical examination and pulse oximetry screening in detecting congenital heart disease in new-borns. Aim: To evaluated the accuracy of pulse oximetry screening for early detection of congenital heart disease.Subjects and Methods: The term new-born babies born during the study period of 12 months had a thorough clinical examination on day 2 of life with emphasis on peripheral pulses, cyanosis, tachypnea, cardiac pulsations and murmurs. Pulse oximetry screening was done within 4hrs of birth and at 48-72hrs of life. Chest X- ray, ECG and Echocardiogram were done for those babies with either abnormal clinical examination or pulse oximetry reading. Clinical examination was done again 2 weeks after discharge. Results: The sensitivity 26% for oximetry alone and 60% for clinical examination alone. Specificity was 99.8% for pulse oximetry alone, and 98% for clinical examination alone. Conclusion: Pulse oximetry can enhance the clinician’s ability to detect life threatening CHD in a timely manner.