Does assessment of haematological parameters using automated haematology analyser help in diagnosing non-neoplastic lesions of thyroid
Keywords:Haematological parameters, non neoplastic lesions, Thyroid function test.
Background: Thyroid hormones plays an important role in maintenance of metabolism. They are required for differentiation and development of foetus. It has a crucial role in haemoglobin synthesis by regulating haematopoiesis in the bone marrow by increasing the erythropoietin production or by production of erythropoietic factors by non-erythroid cells. Aim of the study: To determine the association between thyroid function tests and haematological parameters using Automated Sysmex XN-1000 haematology analyser. Methods and material: The was retrospective study conducted in the department of Pathology in a tertiary care hospital. About 109 samples were included in the study and subjects were grouped into hypothyroidism and hyperthyroidism. Statistical analysis of data was done by SPSS 25:00 IBM: USA. Results: The study group consisted of 109 patients with mean age 44 years and standard deviation 13.93. There were 78.9% females and 21.1% males. Based on thyroid function status patients were divided into hypothyroidism and hyperthyroidism. The analysis showed a significant association in RBC and WBC parameters with hypothyroidism but there were no association seen between platelet parameters and thyroid hormone levels. Conclusion: The study concluded that females are more affected by thyroid disorders than males and the peak age is in the 5th decade of life. Thyroid dysfunction especially hypothyroidism affects all blood parameters except WBC and platelets. The follow up of patients with thyroid disorders should include the complete blood count and patients diagnosed with anaemia should be evaluated for thyroid function before iron therapy. Cases of anaemia that resist treatment should be investigated for the possibility of thyroid dysfunction.
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Copyright (c) 2021 Prabhina K.P., Purnima S Rao, Prageeth N.P.
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