An Observational study of clinical profile of acute febrile illness during monsoon and post monsoon period in a tertiary centre of Bihar: A Prospective Study

Abstract

Objective: To evaluate aetiology, clinical profile, signs and lab parameters altogether related complicated acute febrile illness among inpatients in a tertiary care clinic during monsoon and post monsoon period. Materials & Method: This was an observational review conducted in a tertiary care and research centre of Bihar. In this review we had incorporated the instance of patients who had admitted in the hospital with acute febrile illness during monsoon and post monsoon period. From clinical records aggregate information of laboratory, clinical, and demographic were gathered in predesigned proforma and examined. Results: Of the 198 cases studied 127 were dengue, 3 were hepatitis E, 29 were malaria, 28 were scrub or bush typhus fever, 6 were leptospirosis, and 5 were mixed infections. over all major common symptoms are body ache (84.8%), headache (74.7%), nausea or vomiting (73.2%) apart of other symptoms like coloured urine (36.9%), abdominal pain (48.5%), diarrhea (15.2%), rash (20.2%) and shortness go breath (33.3%). As per statistical correlation symptoms, shortness of breath (P=0.001), coloured urine (P=0.003), diarrhea (P=0.002) had been noticed whereas other symptoms were not significantly associated. rapid week pulse (32.8%) was most common sign after tachypnoea (22.2%). Tachypnoea (P=0.001) and pedal edema (P=0.001) were clinical signs which were significantly associated with. Renal function parameters were little elevated with elevated serum creatinine and blood urea nitrogen along with high level of SGOT and SGPT. Majority of patients were affected with 3 organ followed by 2 organ and 4 organ damage. Conclusion: Treatment and determination of acute febrile illness were related with major complexity as there were diversity of etiological agents and similar clinical presentations. This study conclude that early referral can led to minimise the morbidity and death related with acute febrile illness during monsoon and post monsoon period. Among acute febrile illness the most prevailing aetiologies were dengue, leptospirosis, scrub or bush typhus fever, malaria and major killer due to renal involvements and respiratory.