Lipid Profile and Correlation with Blood Pressure among People of Bundelkhand, Madhya Pradesh

Abstract

Introduction: Hypertension is a major health problem worldwide. Uncontrolled hypertension can cause damage to all organs of body. Dyslipidemia and hypertension are the commonest risk factors for coronary artery disease (CAD). There is a strong association between hypertension and dyslipidemia. They increase patient’s susceptibility to the development of coronary heart disease.Aim: To study the correlation of blood pressure with lipid profile among people of bundelkhand region of Madhya Pradesh.Materials and Methods: A case- control study was conducted in a time span of 1 year from January 2019 to January2020. It was carried out in the Department of Medicine and Biochemistry, Govt. Medical College, Datia Madhya Pradesh. Age and sex matched 75 cases and 30controls were included in study.Results: Total cholesterol, LDL-C were found to be significantly high in hypertensive patients and HDL-C was found to be decreased in hypertensive patients while triglyceride and VLDL-C levels showed no positive correlation with hypertension. In this study total cholesterol was found to be higher in females (205.3±56.3) as compared to males (178.6±51.8) which was statistically significant (p=0.037), all the other lipid fractions ie TG, LDL-C, HDL-C, VLDL-C, were found to be statistically insignificant in both males and females (p value> 0.005). Conclusion: It was concluded that serum lipid profile can serve as an important marker for screening hypertensive patients for cardiovascular diseases, and their early detection can reduce cardiovascular morbidity and mortality.