Evaluating the correlation between Neutrophil-to-Lymphocyte Ratio (NLR) and Child-Turcotte Pugh (CTP) Score for predicting the severity of Decompensated Liver Cirrhosis

Authors

  • JL Wadhwani Associate professor, Department of Medicine, Gandhi Medical College, Bhopal, Madhya Pradesh, India
  • Manuj Sharma Associate professor, Endocrinology Department of Medicine, Gandhi Medical College, Bhopal, Madhya Pradesh, India
  • Anil Sejwar Associate Professor, Department of Medicine, Gandhi Medical College, Bhopal, Madhya Pradesh, India
  • Swapnil Sahu Resident, Department of Medicine, Gandhi Medical College, Bhopal, Madhya Pradesh, India

Keywords:

Child-Pugh Turcotte Score, Neutrophil-to-Lymphocyte Ratio, liver cirrhosis, inflammation

Abstract

Background: The Neutrophil-to-Lymphocyte Ratio (NLR) is a ratio used as a marker of ongoing inflammation and is associated with poor clinical outcomes in patients with liver cirrhosis. Aims and objectives: To determine the correlation between NLR and Child-Turcotte Pugh (CTP) score among decompensated liver cirrhosis patients in a tertiary care center. Materials and methods: A hundred patients with liver cirrhosis (age >18 years) were studied in the Department of Medicine, Gandhi Medical College, Bhopal, from June 2019 to July 2020. Complete blood count and laboratory findings for random and fasting samples were tested and recorded. An NLR was obtained. Child-Pugh Turcotte Score was used to evaluate the severity of liver cirrhosis in Class A (5-6), Class B (7-9), or Class C (10). Results: The majority of the liver cirrhosis patients were males (70%). On person correlation, NLR had a significant positive correlation with CTP score (r=0.572; p=0.002). Conclusion: A significant association was reported between NLR and CPT in assessing the severity of liver cirrhosis. Further research is required before the NLR ratio's potential as a mortality and prognosis predictor can be fully recognized.

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Published

2021-12-24

How to Cite

JL Wadhwani, Manuj Sharma, Anil Sejwar, & Swapnil Sahu. (2021). Evaluating the correlation between Neutrophil-to-Lymphocyte Ratio (NLR) and Child-Turcotte Pugh (CTP) Score for predicting the severity of Decompensated Liver Cirrhosis. International Journal of Health and Clinical Research, 4(23), 89–91. Retrieved from https://ijhcr.com/index.php/ijhcr/article/view/3635