A study to evaluate the role of lipid profile in a patient with cirrhosis and to assess its relationship to the severity of cirrhosis.

Abstract

Aim: to determine role of lipid profile in a patient with cirrhosis and to assess its relationship to the severity of cirrhosis. Methods The present study was conducted in the Department of Biochemistry, Patna. Medical College and Hospital, Patna, Bihar, India from June 2019 to December 2019. Serum lipid profile was observed in these patients. Results: Mean total cholesterol in cirrhotic study group was 144.47+16.10 and in control group was 160.61+15.65. Mean of total cholesterol was higher in control group than in study group that was statistically significant as p value < .00001. Mean LDL cholesterol in cirrhotic study group was 81.50+14.27 and in control group was 91.96+17.75. Mean of LDL cholesterol was higher in control group than in study group that was statistically significant as p value 0.0012. Conclusions: Serum cholesterol and HDL level decreases with progression of cirrhosis. In future serum lipid profile can be used in classification criteria for assessing severity of liver cirrhosis.

Keywords: Chronic liver disease, Lipid profile, Severity of liver cirrhosis