Clinico-pathological study of soft tissue tumors: an observational study

Abstract

Objective: to determine the overall incidence of soft tissue tumours and their frequency of distribution in relation to age, sex and various sites in the body, and to study the histomorphological features which would help in classification and sub classification of soft tissue tumours. Methods: This retrospective study was carried out Department of Pathology, Jawaharlal Nehru Medical College and Hospital Bhagalpur, Bihar, India from January 2019 to December 2019. Total 200 patients of all the soft tissue tumors, both benign and malignant were included in this study. Results: Benign soft tissue tumours formed 87.5% of all soft tissue tumours while malignant soft tissue tumours constituted 12.5% .the male to female ratio among the benign soft tissue tumours was 1.33:1 and among the malignant soft tissue tumours was 1.27:1. The commonest benign tumour was lipoma (52%) of all benign tumours of soft tissue followed by vascular tumours (19.5%) peripheral nerve sheath tumours (18%), fibrous tumours (2.5%), fibrohistiocytic tumours (3.5%) smooth muscle tumours (1.5%) and tumours of uncertain differentiation (1%) in the decreasing order to frequency. There is a highly significant association between the type of tumours and the category of tumours. Conclusion: A careful gross examination of the specimen and adequate sampling of the tumour is essential. Immunohistochemistry and Special stains are helpful in addition to the routine Haematoxylin and eosin for the proper diagnosis of Soft tissue tumours.

Keywords: soft tissue tumors, clinicopathological, adipose