Study of Trabeculectomy with or without Mitomycin C

Abstract

Glaucoma is a group of disorders that are characterized by widely diverse clinical and histopathological manifestations which was apparently recognized by the Greeks as early as 400 B.C. Although an association with elevated intraocular pressure is found in ‘Arabian writings’ in the 10 th century it was not until the 19th century that glaucoma was clearly recognized as a distinct group of ocular disorders. Glaucoma is one of the main blinding disease in our country. According to a World Health Organization report glaucoma is the third most common cause of blindness in the world The sample size was 50 and the study was prospective and non-randomized study. Out of 50 patients 25 patients were posted for simple trabeculectomy (Group A) and 25 patients were posted for trabeculectomy with Mitomycin- C (Group B) after taking their informed written consent. The study comparing the effects of trabeculectomy with and without mitomycin-c in glaucoma patients were undertaken in Department of Ophthalmology, Hitech Medical College and Hospital, during the period of 2019-2021. The overall goal for all glaucoma treatment is to preserve useful vision. Glaucoma is a multifactorial disease but the intraocular pressure is still the only known treatable risk factor. Substantial pressure reduction is difficult to achieve without filtering surgery.