A Prospective observational study on ischemic stroke and impact of thyroid profile at a tertiary care center

Abstract

Background: Stroke is reckoned as a major manifestation of Cardio-Vascular Diseases (CVD) and an alarming reason for long-term disability, mortality, and morbidity in India. Among the widespread endocrine disorders, Thyroid dysfunction tends to influence prognosis and stroke risks in multifarious ways. Aim: The objective of this study is to determine the possible association of serum T3 level with the severity of a stroke and post-stroke recovery. Methodology: This study included 588 patients admitted with the diagnosis of ischemic stroke who had visited the emergency department of the Indira Gandhi Institute of Medical Sciences, Patna. Patients who were above age of 18 were included in the study.
Results: The findings revealed that about 273 (46.42%) patients were diagnosed with the ischemic stroke while 314 (53.40%) patients were diagnosed with haemorrhagic stroke. The average age +SD of the study was 58.2 + 12.4, and the male to female ratio was 1.45:2. Among the common risk factors determined, hypertension (76.65%) was the highest and dyslipidemia was second highest (52.98%), hemiplegia (84.12%) has been found as the most common clinical presentation. Conclusion: Increased levels of TSH might correlate with better functional outcomes, however, a low level of T3/fT3 would correlate with worse outcomes among the patients of acute ischemic stroke (AIS).