Evaluation of Homocysteine Level- A Risk factor among patients with ischaemic Stroke admitted in emergency of tertiary care centre of Bihar

Authors

  • Santosh Kumar Nayan Assistant Professor, Dept. of Trauma and Emergency (General Medicine), IGIMS, Patna, Bihar, India
  • Siddharth Singh Assistant Professor, Dept. of Trauma and Emergency (General Medicine), IGIMS, Patna, Bihar, India
  • Janardan Assistant Professor, Dept. of Neuromedicine, IGIMS, Patna, Bihar, India
  • Sumeet Kumar Assistant Professor, Dept. of Surgery (Trauma and Emergency), IGIMS, Patna, Bihar, India

Keywords:

Homocysteine, ischemic stroke, risk factors, vascular disease

Abstract

Background: Epidemiological investigations have shown that expanded complete homocysteine (tHcy) magnitude are related with an expanded risk of thromboembolic disease; nonetheless, controversy actually exists over which subtype of stroke is associated to hyperhomocysteinemia (HHcy). This investigation meant to examine whether raised tHcy is an autonomous risk factor for ischemic stroke and to contrast tHcy magnitude in patients and ischemic stroke subtypes. Objectives: To decide the recurrence of brought homocysteine level up in ischemic stroke. Methods: This forthcoming observational case control investigation was carried on 133 youthful ischemic stroke patients with 120 control match people over a time of 6 months, from March 2021 to August 2021 at Tertiary Care Centre, Patna. Results: The plasma fasting homocysteine magnitude was altogether higher in the cases than in the controls. The mean homocysteine magnitude was raised altogether in those with cardioembolic strokes contrasted and the controls. The plasma homocysteine level was related with a changed chances proportion of 2.15 for homocysteine over 16 μmol/L fixation for a wide range of stroke. Conclusion: Expanded degree of Serum Homocysteine is altogether connected with risk of cerebrovascular mishap, which is free of the risk credited to conventional risk factors.

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Published

2022-01-18

How to Cite

Santosh Kumar Nayan, Siddharth Singh, Janardan, & Sumeet Kumar. (2022). Evaluation of Homocysteine Level- A Risk factor among patients with ischaemic Stroke admitted in emergency of tertiary care centre of Bihar. International Journal of Health and Clinical Research, 5(3), 110–113. Retrieved from https://ijhcr.com/index.php/ijhcr/article/view/4312