Comparative evaluation of Super-oxidized Solution and Povidone Iodine solution in Management of Infected Diabetic Ulcers

Abstract

Background: Diabetic foot ulcer is a moving issue to each clinician in everyday practice. Super-oxidized Solution is a more up to date idea in the wound management.  Aim: The current investigation was attempted to compare the effectiveness of  super-oxidized preparations and povidone iodine in the management of infected diabetic ulcers. Materials and methods: This prospective study was conducted on a total of 60 patients presenting with infected diabetic ulcers. Patients were divided into two groups of 30 each based on computer generated randomization that is, group A (Topical super-oxidized solution dressing) and group B (Topical povidone iodine dressing). Wound was observed for decrease in size of the ulcer, granulation, tissue quality and discharge from the wound at the end of each week for two weeks. Results: In the present study, 76.67% of patients in group A and B were males and the male to female ratio was 3.2:1. The mean group A was 55.90 ± 14.27 years compared to 51.50 ± 13.18 years in group B. Type 2 diabetes was present in 96.67% and 93.33% of patients in group A and B. The mean initial ulcer area in group A was 3882 ± 1890 mm² compared to 3992 ± 2000 mm² in group B. The mean final area in group A was significantly low (1607 ± 862 mm²) compared to group B (2351 ± 1240 mm²; p=0.009) and the comparison of mean change in ulcer area was significantly high in group A compared to group B (2215 ± 1060 mm² vs 1641 ± 856 mm²; p=0.024). The mean percentage reduction in  ulcer among patients with group A was significantly high (58.90±5.21percent vs.40.90±8.76 percent; p=0.024).The commonest organism isolated in group A was Escherichia coli (26.67%) and in group B, it was staphylococcus. The culture was positive in 26% of the patients in group A compared to 50% in group B (p=0.063).Conclusion : Overall, topical super-oxidized solution dressings accelerated the healing process resulting in faster recovery through reduction in ulcer area in patients infected with diabetic ulcers compared to topical povidone iodine dressing.