A study on serum lipid profile in obese prediabetics

Abstract

Background: Prediabetes is well-known to be a significant risk factor for type 2diabetes as well as heart disease and other chronic conditions. The pattern of multi-system involvement in prediabetes is similar to that of diabetic neuropathy. The purpose of this study was to determine the trend in fasting lipids in obese prediabetics who were obese at baseline. Objective: Obese patients with prediabetes were studied for their serum lipid profile. Materials and Methods: According to the inclusion criteria, this is a prospective case-control research with 40 patients and 40 controls who were admitted to Govt Medical College, Suryapet over 18 months. All of the pertinent information was gathered, and the variables were then examined using the t-test and the chi-square test. Results: Compared to the control group, the mean total cholesterol in the case group was 168.26, which was greater than the control group's 189.24. Triglycerides averaged 176.84mg/dl in the control group of obese patients, whereas they averaged 190.44mg/dl in the obese prediabetic group. However, LDL cholesterol was on the rise. Individuals with prediabetes had a haemoglobin A1C of 115.66, compared to 145.66 in the control group. A higher HDL cholesterol level of 40.34 was found in the control group, compared to a lower HDL cholesterol level of 35.68 in the case group, according to this study. Interestingly, there was no statistically significant difference in VLDL levels across the groups in this investigation. It was discovered that the control group had a mean VLDL of 31.3432. Individuals with obesity and pre- diabetes had a VLDL. Furthermore, when compared to FBS, it was discovered that HbA1c alone was not a sufficient technique for detecting dyslipidemia Conclusion: According to the findings of this study, all serum lipid markers, except for HDL-c, are considerably raised in prediabetic obese patients. Because of their dyslipidemic status, these prediabetic obese adults are at an increased risk of developing cardiovascular disease in the future.