A prospective study of pattern of serum lipid profile of type 2 diabetes patients in a tertiary care hospital

Abstract

Introduction: Diabetes is characterized by chronic hyperglycemia and disturbances of carbohydrate, lipid and protein metabolism. Dyslipidemia is one of the major risk factor for cardiovascular disease in Type 2 Diabetes mellitus, characterized by elevated Total cholesterol (TC), Triglycerides (TG), Low density lipoprotein (LDL) and decreased High density lipoprotein (HDL). Because detection and treatment of dyslipidemia is one means of reducing Cardiovascular Disease (CVD) risk, determination of serum lipid levels in people with diabetes is now considered a standard of care. Materials and Methods: A total of 200 with type 2 diabetes mellitus irrespective of duration of diabetes in the age group of 36-75 years formed the study subjects. A prestructural proforma will be used to collect baseline date detailed clinical history with clinical examination and relevant investigation will be done on participating individuals. Results: During our study we randomly selected 200 Diabetes mellitus-type-2 patients visiting OPD or admitted in the department of Medicine at our institution. Out of 200 DM patients, 60 were Males and 40 were Females. The Mean age of patients in our study was 57.29 +56.55 mg/dl and mean PPBS was 252 +73.76 mg/dl. Conclusion: This study shows significant increasing levels of TG, TC, LDl-C, and Vdl-C and significant decrease in level of HDL-C has the severity of diabetes.