An observational study on serum electrolytes among patients with acute exacerbations of chronic bronchial asthma at a tertiary care hospital of Bihar
Keywords:Serum electrolytes, chronic bronchial asthma
Introduction: Abnormal electrolyte levels in patients with bronchial asthma can be attributed to either low dietary intake or to adverse effects of asthma medications. Hypokalemia has been reported as an electrolyte disturbance in acute asthma. This study was aimed at assessing the levels of serum electrolytes in patients with acute exacerbation of bronchial asthma and comparing them against non-asthmatic controls. Materials and Methods: This observational study was conducted on Department of Biochemistry of, Darbhanga Medical College & Hospital, Laheriasri, Bihar, India from June 2021 to May 2022. The study population comprised of samples obtained in the department from patients who presented with complaints of acute exacerbation of bronchial asthma in the Emergency Department of the hospital. During the study period, samples from a total of 100 asthmatic patients were included. For comparison, I obtained samples from the Emergency department from 100 age and gender matched controls that were not asthmatics. The study was approved by the institutional ethics committee. The data collected were analyzed by SPSS version 20. Results: A total of 200 patients were included in the study, 100 in each group, cases and controls. Both the groups were age and gender matched. The mean (SD) age of cases was 38.9 (14.7) years for cases and 40.4 (12.9) years. There was male preponderance noted in both the groups. T test for age and gender showed a p value of >0.05, that means the groups were comparable. Except for mean serum chloride, all the electrolytes had mean value lower among cases as compared to controls. Among cases, the mean serum sodium, calcium and magnesium were significantly lower than that of control population. Conclusion: The present study showed that there was a significant decrease of sodium, magnesium and calcium levels during exacerbations in asthmatics.
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Copyright (c) 2022 Naresh Kumar Suman, Md. Haroon Rashid, Sude Kumar Singh
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