Prevalence of comorbidities amongest h.pylori-positive patients at a tertiary care hospital, Jammu

Abstract

Introduction: Helicobacter pylori is a gram-negative, microaerophilic bacterium usually found in the stomach. The bacterium is transmitted by feco oral route and is associated with peptic ulcer, duodenal ulcer, and gastric carcinoma. The scope of this study is to determine the prevalence of comorbidities amongest H.pylori-positive patients at a tertiary care hospital, in Jammu, which can give a better picture of the current situation and estimate the at-risk population of gastric carcinoma. Materials and Methods: This was a prospective observational study done at a tertiary healthcare hospital in Jammu, India, over 04 years (March 2016 to March 2020). Written and informed consent regarding the purpose, procedures, and risks was obtained from all patients. Data were collected by conducting a personal interview and doing a complete physical examination of the participants of the study. A structured pro forma was used and filled out after interviewing and examining the patient. The following information was collected for all the participants: age, gender, symptoms, duration, comorbidities, and durations, and any treatment patient has received. Results: Most common comorbidity was hypertension in the study group and among these patients, 138(88.46%) were H pylori positive, 2nd common comorbidity was Diabetes mellitus and among them 133(91.86%) were H pylori positive and 04 patients had CRPF and all of them were H pylori positive. Conclusion: Among all symptomatic patients enrolled in this study the most symptom was epigastric pain followed by dyspepsia and the most common comorbidities in the study group were HTN and Diabetes mellitus. A rapid urease test was performed on UGI endoscopic biopsy specimen for H pylori infestation and 78.5% of patients were found to be positive.