Formulation and evaluation of fast dissolving tablet-bilastine

Authors

  • Mohit Changra Department of Pharmaceutics, Himachal Institute of Pharmacy, Paonta sahib, Himachal Pradesh, India
  • Satinder Kakkar Department of Pharmaceutics, Himachal Institute of Pharmacy, Paonta sahib, Himachal Pradesh, India
  • Ramandeep Singh Department of Pharmaceutics, Himachal Institute of Pharmacy, Paonta sahib, Himachal Pradesh, India

Keywords:

Bilastine, Fast dissolving tablets, NSAIDs.

Abstract

In the present, study to establish Fast dissolving tablets of Bilastine by using different ratio of superdisintegrants. The tablets were prepared by using two superdisintegrants( croscarmellose sodium, sodium starch glycolate) in different composition. Development of Fast dissolving tablets of Bilastine were designed to give rapid onset of action and help those patients who have difficulty in swallowing the drug . The present study aims to improve patient compliance, reduce the condition of dysphagia and also reduces the multiple dosing. Tablets were evaluated by different parameters such as Weight variation, Tablet hardness, Friability ,Mouth feel ,Wetting time, Water absorption ratio, In vitro drug release study, In vitro disintegration time, Drug content uniformity, Accelerated stability testing. The present study concludes that fast dissolving tablets of Bilastine with different composition of superdisintrgants shows rapid disintregation time as well as dissolution profile which represents rapid onset of action of the formulation.

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Published

2024-10-22

How to Cite

Mohit Changra, Satinder Kakkar, & Ramandeep Singh. (2024). Formulation and evaluation of fast dissolving tablet-bilastine. International Journal of Health and Clinical Research, 7(4), 10–14. Retrieved from https://ijhcr.com/index.php/ijhcr/article/view/5476