Study the prevalence of dyslipidemia in STEMI patients with its correlation to thyroid dysfunction

Abstract

Introduction:Thyroid hormones play a major role in the cardiovascular system functioning and in  maintaining the cardiovascular homeostasis through direct and indirect mechanisms. A slight change in the thyroid status affects cardiovascular mortality.It also regulate the enzymes involved in all steps of lipid metabolism leading to the development of qualitative and quantitative changes of lipids in thyroid disease. We tried to evaluate the prevalence of thyroid dysfunction in STEMI patients  and to study the impact of these dysfunctions on morbidity and  mortality among those  subjectsand also to find  the occurrence of dyslipidemia in STEMI patients with its correlation to thyroid dysfunction. Method: We did an observational study on 200 patients from April 2019 to June 2020 in our department(SGMH,Rewa) via fulfilling the criteria. Observation & Results: Patients of STEMI had a statistically significant prevalence of dyslipiemia  in  overt and subclinical hypothyroid patients.In this study out of 200 patients 17% of patients had hypothyroidism and 8% had subclinical hypoythyroidism.Conclusion:With high statistical significance of dyslipidemia and thyroid dysfunction in STEMI  patients,earlier risk stratification, diagnosis, lifestyle changes and management could reduce the morbidity and mortality.