To evaluate the effect of Maternal Vitamin D Deficiency on Increased Risk for Hyperbilirubinemia in Term Newborns: an observational study

Abstract

Aim:  to study the effect of Maternal Vitamin D Deficiency on Increased Risk for Hyperbilirubinemia in Term Newborns. Materials and Methods: This prospective observational study was carried out in the Department of Pediatrics, Nalanda Medical College and Hospital at Patna, Bihar India from July 2019 to march 2020 .Serum 25-hydroxyvitamin D was measured from 200 included pregnant women during birth time. The level of bilirubin was measured in their newborns at 3rd to 5th days of life. Results: The level of 25-hydroxyvitamin D was low in 190 (95%) pregnant women. Hyperbilirubinemia was detected in 29 (14.5%) newborns at the 3rd to 5th days of life. Maternal vitamin D during pregnancy showed a significant correlation with the levels of bilirubin in newborns(r= - 0.449, P<0.001). Conclusion: The presence of maternal vitamin D deficiency could effectively predict the increased risk for neonatal Hyperbilirubinemia.

Keywords: Hyperbilirubinemia, Jaundice, Mothers, Newborns, Vitamin D deficiency.