Intrahepatic cholestasis of pregnancy: An evaluation case-control study of perinatal outcome

Authors

  • Neeru Sharma Professor, Department of Gynecology and Obstetrics, Institute for Medical Sciences and Research Centre, Jaipur National University, Jaipur, Rajasthan, India
  • Meeta Gupta Associate Professor, Department of Gynecology and Obstetrics, Institute for Medical Sciences and Research Centre, Jaipur National University, Jaipur, Rajasthan, India

Keywords:

Intrahepatic cholestasis of pregnancy, obstetric cholestasis, preterm labor, perinatal outcome.

Abstract

Objectives: Intrahepatic cholestasis of pregnancy has been identified with a high recurrence of strange intrapartum fetal pulse, amniotic liquid meconium, rashness, and perinatal mortality. To decide if these unfavorable perinatal results could be improved with dynamic intercession, we assessed our outcomes. Study Design: We report an evaluation case-control investigation of 320 sequential patients 9 with intrahepatic cholestasis of pregnancy the executives with antepartum testing and dynamic mediation over a 2-year time span. Results: Our outcomes demonstrate a higher incidence of meconium staining in amniotic liquid at conveyance (25% V9 16%, p < 0.05) and spontaneou9 preterm conveyance (12.1% versus 3.9%, p < 0.05), without an expansion in the recurrence of the anomalous intrapartum fetal pulse (12% versus 11%, not critical), 5-minute Apgar score< 7 (2.0 versus 1.09), not huge), or perinatal mortality (18/1000 versus 13/1000, not critical). End: Antenatal testing and planned intercession of patients with intrahepatic cholestasis of pregnancy are related to a decrease of the recently revealed unfriendly perinatal results.

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Published

2021-01-29

How to Cite

Sharma, N., & Gupta, M. (2021). Intrahepatic cholestasis of pregnancy: An evaluation case-control study of perinatal outcome. International Journal of Health and Clinical Research, 4(2), 253–257. Retrieved from https://ijhcr.com/index.php/ijhcr/article/view/823