A Hospital Based Study to Evaluate the Management of Psoriasis Arthritis and Recovery of Lesions

Abstract

Background: Psoriatic arthritis (PsA) is an inflammatory pathology involving joints and has chronicity; occurring patients affected with psoriasis. Hence; the present study was undertaken for evaluating the Management of Psoriasis Arthritis and Recovery of Lesions. Materials &Methods: A total of 18 patients with presence of PsA were enrolled. Complete demographic details of all the patients were obtained. All the patients were divided into three study groups depending upon type of treatment done as follows: Group A: patients treated with Sulfasalazine,Group B: patients treated with biological therapy (TNFα), and Group C: Patients treated with Leflunomide. Comparison with pre-treatment clinical profile was done and resolution was categorized as follows: Complete resolution: Complete resolution of clinical symptoms, Significant resolution: Resolution of more than 50 percent of the clinical symptoms, Insignificant resolution: Resolution of less than 50 percent of the clinical symptoms and No effect: Absence of any type of clinical improvement. All the results were recorded and analysed. Statistical analysis was done using SPSS software. Results: Insignificant resolution occurred in 2 patients of group A, 2 patients of group B and 2 patient of group C. No effect was seen in 1 patient of group A, 1 patient of group B and 3 patients of group C. Conclusion:Sulfasalazine and biological therapy significantly results in resolution of the lesions in PsA patients.