To Study the Prevalence of Asymptomatic Bacteriuria and other uropathogens in diabetic patients in a tertiary care hospital-A Prospective study

Abstract

Introduction: Asymptomaticbacteriuria (ASB) is defined as the presence of at least >105 colony forming units (CFU) per ml of 1 or 2 bacterial species in clean-voided midstream urine sample from an individual without symptoms of a urinary tract infection like dysuria, frequency, urgency, abdominal distention or fever.E.coli,K. pneumonia, P.mirabilis, P.aeruginosa, S. saprophyticus, E.faecalis are the leading cause of ASB. Aims and objectives: To study the prevalence of bacteriuria and other uropathogens in patients of diabetes mellitus, association of ASB with age ,gender,duration and complications of diabetes. Materials and method:120diabetic patients were studied.Thereurinalysis, FBS,PPBS,AST,routine investigations and USG abdomen were analysed. Data analysis using SPSS software. Result: Prevalence of ASB amongst diabetic patients was found to be 25.83%(31/120).Most of the participants were in the age group of 41-50 years .Female and males were 56.66% and 43.33% respectively. Maximum participants were having >10 yrsduration of diabetes. There was significant correlation of ASB with nephropathy with p value 0.002.Proteinuria,leucocyturia and glucosuria were also significant, tested by fischer exact test .There was no significant correlation of ASB with age ,gender, duration of diabetes and type of diabetes. E.coli was the uropathogen isolated in our study followed by Klebsiella and candida. Conclusion: The prevalence of ASB in diabetes was 25.83%. E.coli, Klebsiella and Candida were the pathogens commonly identified. There was significant association with glucosuria ,proteinuria, leukocyturia and nephropathy with ASB.