A study to assess the lipid patterns and association of AIP with HbA1c in diabetes patients

Abstract

Aim: There is lack of data regarding lipid patterns and the relationship of the atherogenic index of plasma (AIP) with glycemic control in Indian diabetes patients. This study aimed to assess the lipid patterns and association of AIP with HbA1c in diabetes patients Shri krishna Medical College and Hospital, Muzaffarpur, Bihar, India. Methods: This study conducted in the Department of Medicine, Shri Krishna Medical College and Hospital, Muzaffarpur, Bihar, India for 1 year.  Total 160 diagnosed cases of DM type 2 in the age group of 20-70 years were included in this study. The patients were divided into 2 groups depending on the levels of glycated hemoglobin. Venous blood samples from all the subjects were collected after at least 6 hours fasting and analyzed for fasting plasma glucose (FPG), 2 hours post prandial  glucose levels(2hPG), serum total cholesterol(TC), triglycerides(TG),HDL-C, Very low density lipoprotein cholesterol(VLDL-C) & LDL-C analysis was done by standard methods.The atherogenic index of plasma (AIP) was calculated by the formula base 10 logarithm of the ratio of TG to HDL-C.Results: Out of the 160 patients studied, there were 70 males and 90 females. Conclusion: It can be concluded from the present study that patients with poor glycemic control have a atherogenic lipid profile and Glycated haemoglobin predicts dyslipidemia and atherogenicity.

Keywords: Lipid profile, type 2 diabetes mellitus, Glycosylated haemoglobin, glycemic control, atherogenic index of plasma.