A Study to Evaluate the Effects of Single Dose of Intravenous Dexmedetomidine on Hyperbaric Bupivacaine

Abstract

Aim : The present study was designed to evaluate the effects of single bolus dose of intravenous Dexmedetomidine on spinal anaesthesia and analgesia in patients undergoing below umbilical surgeries with 0.5% Hyperbaric Bupivacaine. Methods: Sixty patients posted for below umbilical surgeries were randomly allocated to two groups. Group D - single bolus dose of 0.5mcg/kg of Dexmedetomidine and Group C - 100 ml of normal saline. Variation in the sensorimotor parameters, effect on sedation and side effects were recorded. Results: The onset of sensory and motor block was significantly earlier in Group D (2.20 ± 0.80 min, 2.17±0.53 min) as compared to Group C (4.33 ± 0.84 min, 3.87 ± 0.62 min). Sedation score and incidence of bradycardia was high in Group D when compared to Group C. Conclusion: Single bolus dose of IV Dexmedetomidine prior to spinal anaesthesia prolongs the duration of sensory block and duration of analgesia with satisfactory arousable sedation and acceptable side effects.